Immunogen sequence: THLSSTEAFCV FYHLKSNPSV FLCQCSCYVA EDQQYQWLEK VFGSCPRKNM QITILTCRHV TDYKTSESTG SLPSPF
Highest antigen sequence identity to the following orthologs - mouse 77%, rat 75%.
Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C21-LRP; C21LRP; Chromosome 21 leucine-rich protein; Down syndrome critical region gene 2; Down syndrome critical region protein 2; DSCR2; leucine rich protein C21-LRP; LRPC21; macropain) assembly chaperone 1; PAC-1; PAC1; proteasome (prosome; proteasome (prosome, macropain) assembly chaperone 1; proteasome assembling chaperone 1; Proteasome assembly chaperone 1; PSMG1
Gene Aliases: C21LRP; DSCR2; LRPC21; PAC-1; PAC1; PSMG1
UniProt ID: (Human) O95456
Entrez Gene ID: (Human) 8624