Positive Control: 293T, A431, human PSRC1-transfected 293T
Predicted Reactivity: Rhesus Monkey (95%), Bovine (86%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
PSRC1 is required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate, and for normal rate of chromosomal segregation during anaphase. Plays a role in the regulation of mitotic spindle dynamics. Increases the rate of turnover of microtubules on metaphase spindles, and contributes to the generation of normal tension across sister kinetochores. Recruits KIF2A and ANKRD53 to the mitotic spindle and spindle poles. May participate in p53/TP53-regulated growth suppression.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DDA3; differential display and activated by p53; FP3214; MGC1780; p53-regulated DDA3; proline/serine-rich coiled-coil 1; Proline/serine-rich coiled-coil protein 1; PSRC1
Gene Aliases: 5430413I02Rik; AL033312; DDA3; FP3214; PSRC1