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Product Details
PA5-112676
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Platelet-activating factor receptor protein (297-342AA)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Wet ice
RRID
AB_2867411
Target Information
PTAFR shows structural characteristics of the rhodopsin gene family and binds platelet-activating factor (PAF). PAF is a phospholipid (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) that has been implicated as a mediator in diverse pathologic processes, such as allergy, asthma, septic shock, arterial thrombosis, and inflammatory processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: PAF receptor; PAF-R; Platelet-activating factor receptor
Gene Aliases: PAFR; PTAFR
UniProt ID: (Human) P25105, (Mouse) Q62035
Entrez Gene ID: (Human) 5724, (Mouse) 19204
lipopolysaccharide binding
lipopolysaccharide receptor activity
G-protein coupled receptor activity
platelet activating factor receptor activity
phospholipid binding
G-protein coupled purinergic nucleotide receptor activity
mitogen-activated protein kinase binding
signal transducer activity
G-protein coupled receptor
cytokine production
regulation of transcription from RNA polymerase II promoter
chemotaxis
inflammatory response
immune response
G-protein coupled receptor signaling pathway
parturition
response to symbiotic bacterium
positive regulation of phospholipase C activity
lipopolysaccharide-mediated signaling pathway
positive regulation of tumor necrosis factor production
inositol trisphosphate biosynthetic process
G-protein coupled purinergic nucleotide receptor signaling pathway
positive regulation of neutrophil degranulation
transcytosis
positive regulation of interleukin-6 biosynthetic process
positive regulation of translation
negative regulation of blood pressure
positive regulation of vasoconstriction
positive regulation of vasodilation
phosphatidylinositol-mediated signaling
positive regulation of smooth muscle cell proliferation
interferon-gamma-mediated signaling pathway
positive regulation of inositol phosphate biosynthetic process
cellular response to gravity
cellular response to cAMP
cellular response to fatty acid
response to dexamethasone
positive regulation of voltage-gated chloride channel activity
positive regulation of leukocyte tethering or rolling
positive regulation of sensory perception of pain
positive regulation of transcytosis
positive regulation of maternal process involved in parturition
positive regulation of gastro-intestinal system smooth muscle contraction
cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine
pattern recognition receptor signaling pathway
signal transduction
response to lipopolysaccharide
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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