PTAFR shows structural characteristics of the rhodopsin gene family and binds platelet-activating factor (PAF). PAF is a phospholipid (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) that has been implicated as a mediator in diverse pathologic processes, such as allergy, asthma, septic shock, arterial thrombosis, and inflammatory processes.
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Protein Aliases: PAF receptor; PAF-R; Platelet-activating factor receptor
Gene Aliases: PAFR; PTAFR
Molecular Function: G-protein coupled receptor