|Tested species reactivity||Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues K(269) K I N Y Q V D S W E(279) of mouse PTCH.|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-23381 detects Patched (PTCH) in mouse samples. This antibody is expected to cross-react with rat, chicken, and human due to 100% sequence homology.
PA1-23381 has been successfully used in Western blot procedures.
The PA1-23381 immunogen is a synthetic peptide corresponding to residues K(269) K I N Y Q V D S W E(279) of mouse PTCH.
Mutations of the human Patched tumor suppressor gene (PTCH) have been identified in individuals with the nevoid basal cell carcinoma syndrome (NBCCS) as well as in sporadic basal cell carcinomas and medulloblastomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.