PA1-32793 detects PTGDR from human samples.
PA1-32793 has been successfully used in immunohistochemistry (paraffin tissue) applications.
The PA1-32793 immunogen is a synthetic peptide, KLH conjugated.
Store at 4°C short term. For extended storage, aliquot and store at -20°C, avoiding freeze/thaw cycles.
The protein encoded by this gene is a G-protein-coupled receptor. It has been shown to function as a prostanoid DP receptor. The activity of this receptor is mainly mediated by G-S proteins that stimulate adenylate cyclase resulting in an elevation of intracellular cAMP and Ca2+. Knockout studies in mice suggest that the ligand of this receptor, prostaglandin D2 (PGD2), functions as a mast cell-derived mediator to trigger asthmatic responses.
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Protein Aliases: AS1; ASRT1; MGC49004; PGD receptor; PGD2 receptor; Prostaglandin D2 receptor; prostaglandin D2 receptor (DP); Prostanoid DP receptor
Gene Aliases: AS1; ASRT1; DP; DP1; PTGDR; PTGDR1
UniProt ID: (Human) Q13258
Entrez Gene ID: (Human) 5729