Proteintech

PTGES2 Polyclonal Antibody

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PTGES2 Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent analysis of HepG2 cells using 10881-1-AP (PTGES2 antibody) at dilution of 1:25 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).

PTGES2 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using 10881-1-AP (PTGES2 Antibody) at dilution of 1:50 (under 40x lens).

PTGES2 Antibody in Western Blot (WB) — Human stomach tissue were subjected to SDS PAGE followed by western blot with 10881-1-AP (PTGES2 antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours.

PTGES2 Antibody in Immunoprecipitation (IP) — IP result of anti-PTGES2 (IP:10881-1-AP, 4ug; Detection:10881-1-AP 1:500) with mouse heart tissue lysate 4000ug.

Product Details

10881-1-AP

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:1,000	View 3 publications 3 publications
Immunohistochemistry (IHC)	-	View 2 publications 2 publications
Immunohistochemistry (Paraffin) (IHC (P))	1:20-1:200	-
Immunocytochemistry (ICC/IF)	1:10-1:100	-
Immunoprecipitation (IP)	0.5-4.0 µg	-

Product Specifications
Species Reactivity	Human, Mouse, Rat
Published species	Human, Plant
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	PTGES2 Fusion Protein Ag1329 (1-377 aa encoded by BC011613) View immunogen
Conjugate	Unconjugated
Form	Liquid
Concentration	0.13 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.3, with 50% glycerol
Contains	0.02% sodium azide
Storage conditions	-20°C

Product Specific Information

Immunogen sequence: MDPAARVVR ALWPGGCALA WRLGGRPQPL LPTQSRAGFA GAAGGPSPVA AARKGSPRLL GAAALALGGA LGLYHTARWH LRAQDLHAER SAAQLSLSSR LQLTLYQYKT CPFCSKVRAF LDFHALPYQV VEVNPVRRAE IKFSSYRKVP ILVAQEGESS QQLNDSSVII SALKTYLVSG QPLEEIITYY PAMKAVNEQG KEVTEFGNKY WLMLNEKEAQ QVYGGKEART EEMKWRQWAD DWLVHLISPN VYRTPTEALA SFDYIVREGK FGAVEGAVAK YMGAAAMYLI SKRLKSRHRL QDNVREDLYE AADKWVAAVG KDRPFMGGQK PNLADLAVYG VLRVMEGLDA FDDLMQHTHI QPWYLRVERA ITEASPAH (1-377 aa encoded by BC011613)

Target Information

The protein encoded by this gene is a membrane-associated prostaglandin E synthase, which catalyzes the conversion of prostaglandin H2 to prostaglandin E2. This protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE). Multiple transcript variants have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Coupling of oxidative stress responses to tricarboxylic acid cycle and prostaglandin E₂ alterations in Caenorhabditis elegans under extremely low-frequency electromagnetic field.

International journal of radiation biology

Sun Y,Shi Z,Wang Y,Tang C,Liao Y,Yang C,Cai P

Sat Dec 01 00:00:00 EST 2018

Prostaglandin E2 triggers cytochrome P450 17α hydroxylase overexpression via signal transducer and activator of transcription 3 phosphorylation and promotes invasion in endometrial cancer.

Oncology letters

Ke J,Shen Z,Li M,Peng C,Xu P,Wang M,Zhu Y,Zhang X,Wu D

Mon Oct 01 00:00:00 EDT 2018

Prostaglandin E2 (PGE2) promotes proliferation and invasion by enhancing SUMO-1 activity via EP4 receptor in endometrial cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Ke J,Yang Y,Che Q,Jiang F,Wang H,Chen Z,Zhu M,Tong H,Zhang H,Yan X,Wang X,Wang F,Liu Y,Dai C,Wan X

Thu Sep 01 00:00:00 EDT 2016

Prostaglandin E2 (PGE2) promotes proliferation and invasion by enhancing SUMO-1 activity via EP4 receptor in endometrial cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Ke J,Yang Y,Che Q,Jiang F,Wang H,Chen Z,Zhu M,Tong H,Zhang H,Yan X,Wang X,Wang F,Liu Y,Dai C,Wan X

Thu Sep 01 00:00:00 EDT 2016

Effect of propofol on prostaglandin E2 production and prostaglandin synthase-2 and cyclooxygenase-2 expressions in amniotic membrane cells.

Journal of anesthesia

Kim JD,Ahn BM,Joo BS,Kwon JY,Chung HJ,Yu SB

Mon Dec 01 00:00:00 EST 2014

Bioinformatics

Protein Aliases: FLJ14038; gamma-interferon-activated transcriptional element-binding factor 1; GATE-binding factor 1; GBF-1; membrane-associated prostaglandin E synthase 2; Membrane-associated prostaglandin E synthase-2; MGC11289; Microsomal prostaglandin E synthase 2; microsomal prostaglandin E synthase-2; mPGE synthase-2; mPGES-2; Prostaglandin E synthase 2; Prostaglandin E synthase 2 truncated form; Prostaglandin-H(2) E-isomerase; RP11-395P17.2

Gene Aliases: 0610038H10Rik; C79137; C9orf15; GBF-1; GBF1; mPGES-2; Mpges2; PGES2; PTGES2

UniProt ID: (Human) Q9H7Z7, (Mouse) Q8BWM0

Entrez Gene ID: (Human) 80142, (Rat) 311865, (Mouse) 96979

Molecular Function: reductase