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PTGES2 Antibody (PA5-22213) in WB
Western Blot analysis of PTGES2 was performed by separating 30 µg of various whole cell extracts by 10% SDS-PAGE. Proteins were transferred to a membrane and probed with a PTGES2 Polyclonal Antibody (Product # PA5-22213) at a dilution of 1:1000 and a HRP-conjugated anti-rabbit IgG secondary antibody.
Product Details
PA5-22213
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 106 and 343 of PTGES2 (Uniprot ID#Q9H7Z7)
Conjugate
Form
Liquid
Concentration
0.44 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_11154153
Product Specific Information
Recommended positive controls: 293T, HepG2, Molt-4, Raji.
Predicted reactivity: Mouse (89%), Rat (88%), Dog (92%), Chimpanzee (100%), Bovine (87%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The PTGES2 gene encodes for the enzyme prostaglandin E synthase 2 (PTGES2), which is crucial for the biosynthesis of prostaglandin E2 (PGE2) from arachidonic acid. This enzyme operates downstream of the cyclooxygenase (COX) pathway, particularly interacting with COX-1 and COX-2 enzymes. PTGES2 is involved in various physiological and pathological processes by generating PGE2, which functions in inflammation, fever generation, and pain. Notably, PTGES2 is a membrane-associated protein and is distinct in its role compared to other prostaglandin synthases due to its specific functional and regulatory properties. Its activity is essential in fine-tuning the levels of PGE2 in tissues, impacting numerous signaling cascades, including those involved in immune responses and vascular functions.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ14038; gamma-interferon-activated transcriptional element-binding factor 1; GATE-binding factor 1; membrane-associated prostaglandin E synthase 2; Membrane-associated prostaglandin E synthase-2; MGC11289; Microsomal prostaglandin E synthase 2; microsomal prostaglandin E synthase-2; mPGE synthase-2; mPGES-2; Prostaglandin E synthase 2; Prostaglandin-H(2) E-isomerase; RP11-395P17.2
Gene Aliases: C9orf15; GBF-1; GBF1; mPGES-2; PGES2; PTGES2
UniProt ID: (Human) Q9H7Z7
Entrez Gene ID: (Human) 80142
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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