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PTGIR Antibody (PA5-120645) in IHC (P)
Immunohistochemistry analysis of PTGIR in paraffin-embedded human gastric cancer. Samples were incubated with PTGIR Polyclonal antibody (Product # PA5-120645) using a dilution of 1:200 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
PA5-120645
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 207-386 of human PTGIR (NP_000951.1).
Conjugate
Form
Liquid
Concentration
0.46 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2914217
Product Specific Information
Positive test controls include: Mouse eye, Mouse liver. The target is usually found in the following locations: Cell membrane, Multi-pass membrane protein.^M
^M
Immunogen sequence: TLSLCRMYRQ QKRHQGSLGP RPRTGEDEVD HLILLALMTV VMAVCSLPLT IRCFTQAVAP DSSSEMGDLL AFRFYAFNPI LDPWVFILFR KAVFQRLKLW VCCLCLGPAH GDSQTPLSQL ASGRRDPRAP SAPVGKEGSC VPLSAWGEGQ VEPLPPTQQS SGSAVGTSSK AEASVACSLC
Target Information
Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: IP receptor; PGI receptor; PGI2 receptor; Prostacyclin receptor; prostaglandin I receptor (IP); Prostaglandin I2 receptor; Prostanoid IP receptor
Gene Aliases: IP; PGI2; PRIPR; PTGIR
UniProt ID: (Human) P43119, (Mouse) P43252, (Rat) P43253
Entrez Gene ID: (Human) 5739, (Mouse) 19222, (Rat) 292661
inflammatory response
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
cell-cell signaling
negative regulation of platelet-derived growth factor receptor signaling pathway
positive regulation of cAMP biosynthetic process
response to lipopolysaccharide
positive regulation of GTPase activity
positive regulation of cAMP-mediated signaling
negative regulation of smooth muscle cell proliferation
cellular response to prostaglandin D stimulus
signal transduction
G-protein coupled receptor signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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