Recommended positive controls: A549, HeLa, HepG2.
Predicted reactivity: Mouse (99%), Rat (98%), Xenopus laevis (81%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
PTP PEST is an 88 kDa cytosolic protein tyrosine phosphatase which is ubiquitiously expressed in mammalian tissues. PTP PEST exhibits a high specific activity when assayed in vitro with artificial tyrosine-phosphorylated substrates. PTP PEST is subject to regulation via phosphorylation of ser 39 and is catalyzed by both protein kinase C and protein kinase A.
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For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: pest; Protein-tyrosine phosphatase G1; PTP-PEST; PTPG1; tcag7.1075; Tyrosine-protein phosphatase non-receptor type 12
Gene Aliases: PTP-PEST; PTPG1; PTPN12; RKPTP
UniProt ID: (Human) Q05209