Search
Invitrogen
PTPN12 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
PA5-27733
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Published species
Bovine
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of human PTPN12. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.93 mg/mL
Amount
93 µg
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: A549, HeLa, HepG2.
Predicted reactivity: Mouse (99%), Rat (98%), Xenopus laevis (81%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
PTP PEST is an 88 kDa cytosolic protein tyrosine phosphatase which is ubiquitiously expressed in mammalian tissues. PTP PEST exhibits a high specific activity when assayed in vitro with artificial tyrosine-phosphorylated substrates. PTP PEST is subject to regulation via phosphorylation of ser 39 and is catalyzed by both protein kinase C and protein kinase A.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: pest; Protein-tyrosine phosphatase G1; PTP-PEST; PTPG1; tcag7.1075; tumor suppressor; tumor suppressor; pTP; Tyrosine-protein phosphatase non-receptor type 12; unnamed protein product
Gene Aliases: PTP-PEST; PTPG1; PTPN12; RKPTP
UniProt ID: (Human) Q05209
Entrez Gene ID: (Human) 5782, (Rat) 117255
protein dephosphorylation
peptidyl-tyrosine dephosphorylation
regulation of epidermal growth factor receptor signaling pathway
tissue regeneration
cellular response to epidermal growth factor stimulus
negative regulation of ERBB signaling pathway
negative regulation of platelet-derived growth factor receptor-beta signaling pathway
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support