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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
The antibody detects endogenous levels of total PTPN4 protein.
The protein encoded by this gene is a member of the protein tyrosine phosphatase family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. This PTP has been shown to interact with glutamate receptor delta 2 and epsilon subunits, and is thought to play a role in signaling downstream of the glutamate receptors through tyrosine dephosphorylation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MEG; Protein-tyrosine phosphatase MEG1; PTP PTPMEG1; Testis-enriched protein tyrosine phosphatase; Tyrosine-protein phosphatase non-receptor type 4
Gene Aliases: hPTP-MEG; Ptn4; PTPMEG; PTPN4; TEP; TEP/mPTPMEG
UniProt ID: (Mouse) Q9WU22
Entrez Gene ID: (Mouse) 19258
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