|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 22-51 amino acids from human PTPN7|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PTPN7 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPN7 is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The noncatalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP has been shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which is thought to function through dephosphorylating the molecules related to MAP kinase pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BPTP-4; dual specificity phosphatase 1; Hematopoietic protein-tyrosine phosphatase; HEPTP; LC-PTP; LPTP; Protein-tyrosine phosphatase LC-PTP; protein-tyrosine phosphatase, nonreceptor-type, stress induced; PTPNI; Tyrosine-protein phosphatase non-receptor type 7
Gene Aliases: BPTP-4; HEPTP; LC-PTP; LPTP; PTPN7; PTPNI
UniProt ID: (Human) P35236
Entrez Gene ID: (Human) 5778
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