Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: FQFLPQVNG HPDPFDEIIL FSLPPALDWD SVHVPGPHAM TIQELVDYVN ARQKQGIYEE YEDIRRENPV GTFHCSMSPG NLEKNRYGDV PCLDQTRVKL TKRSGHTQTD YINASFMDGY KQKNAYIGTQ GPLENTYRDF WLMVWEQKVL VIVMTTRFEE GGRRKCGQYW PLEKDSRIRF GFLTVTNLGV ENMNHYKKTT LEIHNTEERQ KRQVTHFQFL SWPDYGVPSS AASLIDFLRV VRNQQSLAVS NMGARSKGQC PEPPIVVHCS AGIGRTGTFC SLDICLAQLE ELGTLNVFQT VSRMRTQRAF SIQTPEQYYF CYKAILEFAE KEGMVSSGQN LLAVESQ (248-663 aa encoded by BC010863 )
MEG2 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain that shares a significant similarity with yeast SEC14, which is a protein that has phosphatidylinositol transfer activity and is required for protein secretion through the Golgi complex in yeast. This PTP was found to be activated by polyphosphoinositide, and is thought to be involved in signaling events regulating phagocytosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: meg-2; Protein-tyrosine phosphatase MEG2; Protein-tyrosine phosphatase, non-receptor type 9 (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2); PTPase MEG2; PTPase-MEG2; Tyrosine-protein phosphatase non-receptor type 9
Gene Aliases: MEG2; PTPMEG2; PTPN9
UniProt ID: (Human) P43378, (Rat) Q641Z2, (Mouse) O35239
Entrez Gene ID: (Human) 5780, (Rat) 266611, (Mouse) 56294
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