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Product Details
PA5-63030
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PTPRD. Recombinant protein control fragment (Product #RP-103750).
Conjugate
Form
Liquid
Concentration
0.10 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2646130
Product Specific Information
Immunogen sequence: GREVELKPYI AAHFDVLPTE FTLGDDKHYG GFTNKQLQSG QEYVFFVLAV MEHAESKMYA TSPYSDPVVS MDLDPQPITD EEE
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.
Target Information
PTPRD is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: protein tyrosine phosphatase, receptor type, D; protein tyrosine phosphatase, receptor type, delta polypeptide; Protein-tyrosine phosphatase delta; R-PTP-delta; Receptor-type tyrosine-protein phosphatase delta
Gene Aliases: 1110002J03Rik; 3000002J10Rik; B230219D21Rik; HPTP; HPTPD; HPTPDELTA; PTPD; PTPRD; R-PTP-delta; RPTPDELTA
UniProt ID: (Human) P23468, (Mouse) Q64487
Entrez Gene ID: (Human) 5789, (Mouse) 19266
protein dephosphorylation
phosphate-containing compound metabolic process
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
transmembrane receptor protein tyrosine phosphatase signaling pathway
chemical synaptic transmission
neuron differentiation
peptidyl-tyrosine dephosphorylation
positive regulation of dendrite morphogenesis
presynaptic membrane assembly
dephosphorylation
negative regulation of JAK-STAT cascade
regulation of immune response
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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