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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 772 and 946 of Human PTPRH|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-31340 targets PTPRH in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-31340 immunogen is recombinant protein fragment corresponding to a region within amino acids 772 and 946 of Human PTPRH.
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. The extracellular region contains eight fibronectin type III-like repeats and multiple N-glycosylation sites. The gene was shown to be expressed primarily in brain and liver, and at a lower level in heart and stomach. It was also found to be expressed in several cancer cell lines, but not in the corresponding normal tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
protein tyrosine phosphatase, receptor type, H; R-PTP-H; receptor-type tyrosine-protein phosphatase H; SAP1; stomach cancer-associated protein tyrosine phosphatase 1; transmembrane-type protein-tyrosine phosphatase type H