Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: MADGDSGSE RGGGGGPCGF QPASRGGGEQ ETQELASKRL DIQNKRFYLD VKQNAKGRFL KIAEVGAGGS KSRLTLSMAV AAEFRDSLGD FIEHYAQLGP SSPEQLAAGA EEGGGPRRAL KSEFLVRENR KYYLDLKENQ RGRFLRIRQT VNRGGGGFGA GPGPGGLQSG QTIALPAQGL IEFRDALAKL IDDYGGEDDE LAGGPGGGAG GPGGGLYGEL PEGTSITVDS KRFFFDVGCN KYGVFLRVSE VKPSYRNAIT VPFKAWGKFG GAFCRYADEM KEIQERQRDK LYERRGGGSG GGEESEGEEV DED (1-312 aa encoded by BC101735)
This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: PurB beta; purine-rich element binding protein B; Purine-rich element-binding protein B; purine-rich single-stranded DNA-binding protein beta; transcription factor Pur-beta; transcriptional activator protein Pur-beta; Transcriptional regulator protein Pur-beta; Vascular actin single-stranded DNA-binding factor 2 p44 component
Gene Aliases: 2310015K15Rik; AA114818; Cager-2; D11Bwg0414e; pur-beta; PURB; PURBETA
UniProt ID: (Human) Q96QR8, (Mouse) O35295, (Rat) Q68A21
Entrez Gene ID: (Human) 5814, (Mouse) 19291, (Rat) 498407
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