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This antibody is predicted to react with mouse and rat based on sequence homology.
PXK is widely expressed in all tissues examined except in heart. It binds to and modulates brain Na,K-ATPase subunits ATP1B1 and ATP1B3 and may thereby participate in the regulation of electrical excitability and synaptic transmission. However, the protein kinase domain is predicted to be catalytically inactive.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Modulator of Na,K-ATPase; modulator of Na,K-ATPase long form; MONaKA; PX domain-containing protein kinase-like protein; PX ser/thr kinase v2; PX serine/threonine kinase; PXK
Gene Aliases: PXK
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