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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • PMP70 Antibodies

          Bioss

          PXMP1 Polyclonal Antibody

          View all (12) PMP70 antibodies

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          Cite PXMP1 Polyclonal Antibody

          • Antibody Testing Data (2)
          PXMP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          PXMP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          PXMP1 Antibody (BS-8584R) in IHC (P)

          Formalin-fixed and paraffin embedded human cervical carcinoma labeled with Anti-PXMP1/ABCD3/PMP70 Polyclonal Antibody, Unconjugated (bs-8584R) at 1:200 followed by conjugation to the secondary antibody and DAB staining. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          PXMP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PXMP1 Antibody in ELISA (ELISA)
          PXMP1 Polyclonal Antibody

          Product Details

          BS-8584R

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200
          -

          Immunohistochemistry (Frozen) (IHC (F))

          1:100-1:500
          -

          Immunocytochemistry (ICC/IF)

          1:100-1:500
          -

          ELISA (ELISA)

          1:5,000-1:10,000
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          KLH conjugated synthetic peptide derived from human PXMP1, amino acids 51-160.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Protein A

          Storage buffer

          0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol

          Contains

          0.02% ProClin 300

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          Peroxisomes are single membrane organelles which are involved with many important biochemical pathways and are found in almost all eukaryotic cells. Various toxins including, phenols, alcohols, and aldehydes are targeted for modification by peroxisomes. Long chain fatty acid metabolism via beta-oxidation is also mediated by this organelle. Loss of peroxisomal functions may result in diseases such as Zellweger syndrome, hyperpipecolic acidemia, neonatal adrenoleukodystrophy, and infantile Refsum" disease. Peroxisomal membrane protein 70 (PMP70) is an abundant, integral membrane protein of the peroxisome. This protein is induced by treatment with hypolipidemic agents in parallel with peroxisome proliferation and stimulation of the peroxisomal beta-oxidation enzymes.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: 68 kDa peroxisomal membrane protein; 70 kDa peroxisomal membrane protein; 70-kDa peroxisomal membrane protein; ATP-binding cassette sub-family D member 3; ATP-binding cassette, sub-family D (ALD), member 3; dJ824O18.1 (ATP-binding cassette, sub-family D (ALD), member 3 (PMP70, PXMP1)); Peroxisomal membrane protein 1; peroxisomal membrane protein 1 (70kD, Zellweger syndrome); peroxisomal membrane protein, 70 kDa; Peroxisomal membrane protein-1 (70kD); PMP68; PMP70

          View more View less

          Gene Aliases: ABC43; ABCD3; AI313901; AU018866; AW146054; CBAS5; PMP68; PMP70; PXMP1; ZWS2

          View more View less

          UniProt ID: (Human) P28288, (Mouse) P55096, (Rat) P16970

          View more View less

          Entrez Gene ID: (Human) 5825, (Mouse) 19299, (Rat) 25270

          View more View less

          Function(s)
          long-chain fatty acid transporter activity protein binding ATP binding ATPase activity ATPase activity, coupled to transmembrane movement of substances protein homodimerization activity protein self-association nucleotide binding ATP-binding cassette (ABC) transporter
          Process(es)
          fatty acid biosynthetic process fatty acid beta-oxidation peroxisome organization response to organic cyclic compound peroxisomal long-chain fatty acid import response to drug very long-chain fatty acid catabolic process transmembrane transport transport metabolic process
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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