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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • PYCR1 Antibodies

          Proteintech

          PYCR1 Polyclonal Antibody

          1 Reference
          View all (16) PYCR1 antibodies

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          Cite PYCR1 Polyclonal Antibody

          • Antibody Testing Data (4)
          PYCR1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          PYCR1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 4

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          PYCR1 Antibody (22150-1-AP) in ICC/IF

          Immunofluorescent analysis of ( 10% Formaldehyde ) fixed HeLa cells using 22150-1-AP (PYCR1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          PYCR1 Antibody in Immunocytochemistry (ICC/IF)
          PYCR1 Antibody in Western Blot (WB)
          PYCR1 Antibody in Western Blot (WB)
          PYCR1 Antibody in Immunoprecipitation (IP)

          Product Details

          22150-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          View 1 publication 1 publication

          Immunocytochemistry (ICC/IF)

          1:50-1:500
          -

          Immunoprecipitation (IP)

          0.5-4.0 µg
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          PYCR1 Fusion Protein Ag17745 (14-148 aa encoded by BC022244)

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.33 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: ALAKGFTAA GVLAAHKIMA SSPDMDLATV SALRKMGVKL TPHNKETVQH SDVLFLAVKP HIIPFILDEI GADIEDRHIV VSCAAGVTIS SIEKKLSAFR PAPRVIRCMT NTPVVVREGA TVYATGTHAQ VEDGRL (14-148 aa encoded by BC022244)

          Target Information

          This gene encodes an enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. The protein forms a homopolymer and localizes to the mitochondrion. Alternate splicing results in two transcript variants encoding different isoforms.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: P5C reductase 1; P5CR 1; proliferation-inducing protein 45; Pyrroline-5-carboxylate reductase 1, mitochondrial

          View more View less

          Gene Aliases: ARCL2B; ARCL3B; P5C; P5CR; PIG45; PP222; PRO3; PYCR; PYCR1

          View more View less

          UniProt ID: (Human) P32322, (Mouse) Q922W5

          View more View less

          Entrez Gene ID: (Human) 5831, (Mouse) 209027, (Rat) 287877

          View more View less

          Function(s)
          pyrroline-5-carboxylate reductase activity protein binding identical protein binding oxidoreductase activity reductase
          Process(es)
          proline biosynthetic process cellular amino acid biosynthetic process cellular response to oxidative stress regulation of mitochondrial membrane potential oxidation-reduction process L-proline biosynthetic process negative regulation of hydrogen peroxide-induced cell death
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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