This target displays homology in the following species: Cow: 79%; Dog: 93%; Guinea Pig: 92%; Horse: 93%; Human: 100%; Mouse: 85%; Rat: 100%
PYCRL encodes a protein that belongs to the pyrroline-5-carboxylate reductase family of enzymes. Members of this family catalyze the final step in proline biosynthesis, converting pyrroline-5-carboxylate to proline. Glutamate and ornithine are precursors in the synthesis of proline. The protein encoded by this gene is a cytoplasmic enzyme involved in the biosynthesis of proline from ornithine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: P5C reductase 3; P5CR 3; Pyrroline-5-carboxylate reductase 3; Pyrroline-5-carboxylate reductase-like protein
Gene Aliases: PYCR3; PYCRL
UniProt ID: (Human) Q53H96
Entrez Gene ID: (Human) 65263
Molecular Function: reductase