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Invitrogen
PYY Polyclonal Antibody
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Product Details
PA1-9581
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Chicken
/ IgY
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to amino acids 24-36 of human PYY.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
PA1-9581 detects PYY in human, mouse and rat samples.
PA1-9581 has been successfully used in ELISA procedures.
PA1-9581 immunogen is a synthetic peptide corresponding to amino acids 24-36 of human PYY (LRHYNLVTRQRY).
Target Information
Peptide tyrosine-tyrosine amide (3-36), or PYY (3-36), is a major metabolite of the gut hormone PYY and is produced by the action of dipeptidyl peptidase IV on PYY in the intestinal brush border and in the circulation. PYY (3-36) is a potent inhibitor of food intake in rats and humans, acting selectively on the Y2 receptor to inhibit orexigenic NPY neurons in the arcuate nucleus, thus disinhibiting anorexigenic POMC neurons. The anorexigenic effect of PYY (3-36) is additive to that of the co-secreted gut hormone GLP-1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Peptide tyrosine tyrosine; peptide tyrosine-tyrosine (YY); Peptide YY; Peptide YY3-36; Peptide YY3-37; prepro-PYY; PYY; PYY II; PYY-1; PYY-2; PYY-I; PYYI; PYYII
Gene Aliases: GHYY; peptide-YY; PYY; PYY-I; PYY1; RATGHYY; Yy
UniProt ID: (Human) P10082, (Rat) P10631, (Mouse) Q9EPS2
Entrez Gene ID: (Human) 5697, (Rat) 287730, (Mouse) 217212
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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