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Proteintech
Palladin Polyclonal Antibody
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Product Details
10853-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Palladin Fusion Protein Ag1288 (127-510 aa encoded by BC013867)
Conjugate
Form
Liquid
Concentration
0.21 mg/mL
Amount
31.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody, generated against the fragment 999-1383 aa of palladin, recognizes most isoforms of this protein, except isoform 6.
Immunogen sequence: APFFEMKLK HYKIFEGMPV TFTCRVAGNP KPKIYWFKDG KQISPKSDHY TIQRDLDGTC SLHTTASTLD DDGNYTIMAA NPQGRISCTG RLMVQAVNQR GRSPRSPSGH PHVRRPRSRS RDSGDENEPI QERFFRPHFL QAPGDLTVQE GKLCRMDCKV SGLPTPDLSW QLDGKPVRPD SAHKMLVREN GVHSLIIEPV TSRDAGIYTC IATNRAGQNS FSLELVVAAK EAHKPPVFIE KLQNTGVADG YPVRLECRVL GVPPPQIFWK KENESLTHST DRVSMHQDNH GYICLLIQGA TKEDAGWYTV SAKNEAGIVS CTARLDVYTQ WHQQSQSTKP KKVRPSASRY AALSDQGLDI KAAFQPEANP SHLTLNTALV ESEDL (127-510 aa encoded by BC013867)
Target Information
Palladin is a cytoskeletal protein required for organization of normal actin cytoskeleton. Palladin plays roles in establishing cell morphology, motility, cell adhesion and cell-extracellular matrix interactions in a variety of cell types. Palladin may function as a scaffolding molecule with the potential to impact both actin polymerization as well as the assembly of existing actin filaments into higher-order arrays. It binds to proteins that bind to either monomeric or filamentous actin. It localizes at sites where active actin remodeling takes place, such as lamellipodia and membrane ruffles. Palladin's different isoforms may have functional differences. It is also involved in the control of morphological and cytoskeletal changes associated with dendritic cell maturation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 90kDa actin-associated protein palladin; FLJ22190; FLJ38193; FLJ39139; myoneurin; Palladin; palladin isoform; Sarcoma antigen NY-SAR-77; SIH002; unnamed protein product
Gene Aliases: 2410003B16Rik; 6030492A02; CGI-151; CGI151; KIAA0992; MYN; PALLD; PNCA1; SIH002
UniProt ID: (Human) Q8WX93, (Mouse) Q9ET54
Entrez Gene ID: (Human) 23022, (Mouse) 72333
keratinocyte development
epithelial cell morphogenesis
cytoskeleton organization
homophilic cell adhesion via plasma membrane adhesion molecules
axon guidance
cell migration
actin cytoskeleton organization
dendrite self-avoidance
neuron projection development
ruffle organization
positive regulation of podosome assembly
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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