Immunogen sequence: MSVPGPSSPD GALTRPPYCL EAGEPTPGLS DTSPDEGLIE DLTIEDKAVE QLAEGLLSHY LPDLQRSKQA LQELTQNQVV LLDTLEQEIS KFKECHSMLD INALFAEAKH YHAKLVNIRK EMLMLHEKTS KLKKRALKLQ QKRQKEELER EQQREKEFER EKQLTARPAK; Positive Samples: U-87MG, HepG2, DU145, K-562, Rat testis; Cellular Location: Cytoplasm, Endomembrane system, Peripheral membrane protein
The aquaporins are a family of water-selective membrane channels. This gene encodes a member of a subset of aquaporins called the aquaglyceroporins. This protein allows passage of a broad range of noncharged solutes and also stimulates urea transport and osmotic water permeability. This protein may also facilitate the uptake of glycerol in hepatic tissue. The encoded protein may also play a role in specialized leukocyte functions such as immunological response and bactericidal activity. Alternate splicing results in multiple transcript variants.
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Protein Aliases: biogenesis of lysosomal organelles complex-1, subunit 5, pallidin; biogenesis of lysosomal organelles complex-1, subunit 6, pallidin; Biogenesis of lysosome-related organelles complex 1 subunit 6; biogenesis of organelles complex-1, subunit 6, pallidin; BLOC-1 subunit 6; Pallid protein; Pallid protein homolog; Pallidin; pallidin homolog; syntaxin 13 binding protein 1; Syntaxin 13-interacting protein; syntaxin 13-interacting protein pallid
Gene Aliases: BLOC-1; BLOC1S6; BLOS6; HPS9; P2; PA; PALLID; PLDN; Stx13bp1