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Parvalbumin Polyclonal Antibody
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FIGURE: 1 / 4
Parvalbumin Antibody (29312-1-AP150UL) in IHC (P)
Immunohistochemical analysis of paraffin-embedded Mouse cerebellum tissue slide using (Product # 29312-1-AP150UL) (Parvalbumin antibody) at dilution of 1:2,000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).
Product Details
29312-1-AP150UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
150 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Target Information
Parvalbumin (PV) is a calcium binding protein expressed in specific muscle fibers and fast-firing neurons. PV consists of a single, unbranched chain of linked amino acids and belongs to a larger group of EF hand proteins. Studies have demonstrated that parvalbumin acts in the decay of calcium in the contraction/ relaxation cycle of fast twitch muscles. This data has shown a positive correlation between the rate of relaxation and the concentration of parvalbumin. Parvalbumin is also expressed in a specific population of GABAergic interneurones which are thought to play a role in maintaining the balance between excitation and inhibition in the cortex as well as the hippocampus. In amyotrophic lateral sclerosis (ALS) patents, parvalbumin immunoreactivity is specifically absent from neuron populations lost early in ALS.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Alpha-parvalbumin; Alpha-PV; HGNC:9704; MGC116759; parvalbumin; Parvalbumin alpha; PVALB; unnamed protein product
Gene Aliases: D22S749; Parv; PV; Pva; PVALB
UniProt ID: (Human) P20472, (Mouse) P32848
Entrez Gene ID: (Human) 5816, (Mouse) 19293
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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