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Invitrogen
Parvalbumin Polyclonal Antibody
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FIGURE: 1 / 3
Parvalbumin Antibody (PA5-143579) in IHC (P)
Chromogenic immunohistochemistry of Parvalbumin in formalin fixed paraffin embedded rat cerebellum. Samples were stained with Parvalbumin polyclonal antibody (Product # PA5-143579) using a dilution of 1:2,000. Detected in DAB (brown) following the ABC method. Hematoxylin (blue) was used as the counterstain. Parvalbumin antibody detects perikarya and dendrites of Purkinje cells and interneurons throughout th... View More
Product Details
PA5-143579
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
C. elegans
Host/Isotype
Chicken
/ IgY
Class
Polyclonal
Type
Antibody
Immunogen
Full-length recombinant human protein expressed in and purified from E. coli.
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Parvalbumin (PV) is a calcium binding protein expressed in specific muscle fibers and fast-firing neurons. PV consists of a single, unbranched chain of linked amino acids and belongs to a larger group of EF hand proteins. Studies have demonstrated that parvalbumin acts in the decay of calcium in the contraction/ relaxation cycle of fast twitch muscles. This data has shown a positive correlation between the rate of relaxation and the concentration of parvalbumin. Parvalbumin is also expressed in a specific population of GABAergic interneurones which are thought to play a role in maintaining the balance between excitation and inhibition in the cortex as well as the hippocampus. In amyotrophic lateral sclerosis (ALS) patents, parvalbumin immunoreactivity is specifically absent from neuron populations lost early in ALS.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: HGNC:9704; MGC116759; Parvalbumin (calcium binding protein); Parvalbumin alpha
Gene Aliases: D22S749; PALB1; Parv; PV; Pva; PVALB
UniProt ID: (Human) P20472, (Rat) P02625, (Mouse) P32848
Entrez Gene ID: (Human) 5816, (Rat) 25269, (Mouse) 19293
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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