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Pax7 Antibody (600-401-GR7) in WB
Western Blot of Rabbit anti-Pax7 antibody. Lane 1: Opal Pre-stained ladder (p/n MB-210-0500). Lane 2: Mouse muscle protein lysate. Lane 3: C2C12 Lysate (p/n W09-001-GL7). Lane 4: Ms spleen lysate (p/n W10-000-T029). Lane 5: Ms brain lysate (p/n W10-000-T004). Lane 6: HEK293T Lysate (W09-001-GX5). Lane 7: HeLa WCL (p/n W09-000-364). Lane 8: MCF7 Lysate (p/n W09-000-360). Lane 9: Jurkat Lysate (p/n W09-001-370). Lane 10: A431 Lysate (p/n W09-000-361). Lane 11: A549 Lysate (p/n W09-001-372). Lane 12: LNCap Lysate (p/n W09-001-GJ9). Lane 13... View More
Product Details
600-401-GR7
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Pax7 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of Pax7 protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
0.02M potassium phosphate, pH 7.2, with 0.15M NaCl
Contains
0.01% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
A BLAST analysis was used to suggest cross reactivity with Pax7 protein from mouse (100% homology) and human (66.7% homology) for the immunizing sequence. Cross-reactivity with Pax7 from other sources has not been determined.
Target Information
This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ37460; paired box gene 7; Paired box protein Pax-7; paired box transcription factor PAX7; PAX7A
Gene Aliases: Pax-7; Pax7
UniProt ID: (Mouse) P47239
Entrez Gene ID: (Mouse) 18509
chromatin remodeling
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
multicellular organism development
muscle organ development
skeletal muscle tissue development
organ morphogenesis
regulation of cell fate commitment
regulation of gene expression
skeletal muscle satellite cell commitment
spinal cord association neuron differentiation
dorsal/ventral neural tube patterning
positive regulation of histone methylation
regulation of protein binding
skeletal muscle tissue regeneration
positive regulation of transcription from RNA polymerase II promoter
neuron fate commitment
embryonic skeletal system development
cartilage development
muscle tissue morphogenesis
positive regulation of myoblast proliferation
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