|Tested species reactivity||Mouse, Rat|
|Published species reactivity||Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant full length protein (Rat).|
|Contains||0.1% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (Paraffin) (IHC (P))||See 1 publications below|
PA1-22489 detects Perforin in Mouse and Rat samples.
PA1-22489 has been successfully used in Western Blot procedures.
PA1-22489 immunogen corresponds to Recombinant full length protein (Rat)..
Perforin (pore-forming protein) is originally cloned from mouse cytotoxic T-lymphocyte(CTL) . It is a 555-amino acid protein with a 21-amino acid signal peptide. Perforin is a cytolytic mediator produced by killer lymphocytes, and is stored in and released by cytoplasmic granules. Perforin is involved in the killing mediated by CTL, which represents an important mechanism in the immune defense against tumors and virus infections.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
alpha-actin down regulation and perforin loss in uterine natural killer cells from LPS-treated pregnant mice.
PA1-22489 was used in immunohistochemistry - paraffin section to assess the reactivity of perforin and alpha-actin on uterine natural killer cell from LPS-treated pregnant mice.
|Zavan B,do Amarante-Paffaro AM,Paffaro VA||Physiological research (64:427)||2015|