Phospho-IKK epsilon (Ser172) Polyclonal Antibody detects endogenous levels of IKK epsilon only when phosphorylated at Ser172.
IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: I-kappa-B kinase epsilon; IkBKE; IKK-E; IKK-epsilon; IKK-i; IKK-related kinase epsilon; IKKE; IKKI; Inducible I kappa-B kinase; inducible IKappaB kinase; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon; Inhibitor of nuclear factor kappa-B kinase subunit epsilon; KIAA0151
Gene Aliases: AW558201; IKBKE; IKK-E; IKK-i; IKKE; IKKepsilon; IKKI; KIAA0151