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Invitrogen
Phospho-RGS19 (Ser151) Polyclonal Antibody
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Product Details
PA5-64679
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human GAIP (Phospho-Ser151)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 30% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2662192
Product Specific Information
Phospho-RGS19 (Ser151) Polyclonal Antibody detects endogenous levels of RGS19 only when phosphorylated at Ser151.
Target Information
RGS19 inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, predominantly to G(i)-alpha-3. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: calcium/calmodulin-dependent protein kinase I; G alpha interacting protein; G protein signalling regulator 19; G-alpha interacting protein; G-alpha-interacting protein; GAIP; GAIP protein; GS19; guanine nucleotide binding protein alpha inhibiting activity polypeptide 3 interacting protein; Regulator of G-protein signaling 19; regulator of G-protein signalling 19; RGS19
Gene Aliases: 2610042F04Rik; AI324841; AW547781; Camki; GAIP; GNAI3IP; RGS19; RGSGAIP
UniProt ID: (Human) P49795, (Mouse) Q9CX84, (Rat) O70521
Entrez Gene ID: (Human) 10287, (Mouse) 56470, (Rat) 59293
regulation of transcription, DNA-templated
autophagy
G-protein coupled receptor signaling pathway
small GTPase mediated signal transduction
cell death
dorsal/ventral axis specification
cell differentiation
regulation of catenin import into nucleus
positive regulation of GTPase activity
cellular response to organic cyclic compound
negative regulation of canonical Wnt signaling pathway
Wnt signaling pathway involved in somitogenesis
negative regulation of signal transduction
termination of G-protein coupled receptor signaling pathway
biological_process
regulation of G-protein coupled receptor protein signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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