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Invitrogen
Phospho-RPS6KB2 (Ser423) Polyclonal Antibody
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FIGURE: 1 / 1
Phospho-RPS6KB2 (Ser423) Antibody (PA5-105036) in WB
Western blot analysis of Phospho-RPS6KB2 (Ser423) in mouse lung/mouse brain (absence (-) or presence (+) of non-phospho and phospho peptide). Samples were incubated with Phospho-RPS6KB2 (Ser423) polyclonal antibody (Product # PA5-105036).
Product Details
PA5-105036
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human RPS6KB2(Accession Q9UBS0), corresponding to amino acid residues around phosphorylated Ser423.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
sequential chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of p70 S6 Kinase beta only when phosphorylated at Serine 423.
Target Information
RPS6KB2 (p70S6K beta) is a serine/threonine kinase with 2 non-identical kinase catalytic domains which phosphorylates the S6 ribosomal protein and eukaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 70 kDa ribosomal protein S6 kinase 2; p70 ribosomal S6 kinase beta; p70 S6 kinase beta; p70 S6K-beta; p70 S6KB; p70-S6K 2; P70S6K2; Ribosomal protein S6 kinase beta-2; ribosomal protein S6 kinase, 70kD, polypeptide 2; ribosomal protein S6 kinase, 70kDa, polypeptide 2; S6 kinase 2; S6 kinase-related kinase; S6K-beta; S6K-beta-2; serine/threonine-protein kinase 14 beta; Serine/threonine-protein kinase 14B; SRK
Gene Aliases: 70kDa; KLS; p70(S6K)-beta; P70-beta; P70-beta-1; P70-beta-2; p70S6Kb; RPS6KB2; S6K-beta2; S6K2; SRK; STK14B
UniProt ID: (Human) Q9UBS0, (Mouse) Q9Z1M4
Entrez Gene ID: (Human) 6199, (Mouse) 58988
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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