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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:1,000 | - |
Immunocytochemistry (ICC/IF) |
1:400 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Chicken, Hamster, Human, Mouse, Rat, Xenopus, Zebrafish |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Synthetic phosphopeptide corresponding to residues surrounding pThr573 of human p90RSK |
Conjugate |
Unconjugated |
Form |
Liquid |
Purification |
Antigen affinity chromatography |
Storage buffer |
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
Contains |
no preservative |
Storage conditions |
-20°C |
RRID |
AB_10989467 |
It is not recommended to aliquot this antibody.
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 90 kDa ribosomal protein S6 kinase 1; dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1); MAP kinase-activated protein kinase 1; MAP kinase-activated protein kinase 1a; MAPK-activated protein kinase 1; MAPK-activated protein kinase 1a; MAPKAP kinase 1; MAPKAP kinase 1a; MAPKAPK-1; MAPKAPK-1a; MAPKAPK1A; P90-RSK; p90-RSK 1; p90RSK1; p90S6K; pp90RSK1; Ribosomal protein S6 kinase 2 alpha; ribosomal protein S6 kinase alpha 1; Ribosomal protein S6 kinase alpha-1; Ribosomal protein S6 kinase II alpha; ribosomal protein S6 kinase II beta; ribosomal protein S6 kinase polypeptide 1; ribosomal protein S6 kinase, 90kD, polypeptide 1; Ribosomal protein S6 kinase, 90kD, 1; ribosomal protein S6 kinase, 90kDa, polypeptide 1; ribosomal protein S6 kinase, 90kDa, polypeptide 1 L homeolog; Ribosomal S6 kinase 1; RSK-1; S6 kinase II beta; S6 protein kinase (Rsk-1); S6K-alpha 1; S6K-alpha-1; S6KII-alpha; S6KII-beta
Gene Aliases: HU-1; Mapkapk-1a; MAPKAPK1A; p90-Rsk1; p90Rsk; p90Rsk1; p90S6K; RPS6KA; RPS6KA1; RPS6KA1L; RSK; Rsk-1; RSK1; S6K-alpha-1; wu:fc56h07; XELAEV_18012109mg; zgc:152654
UniProt ID: (Chicken) P18652, (Human) Q15418, (Rat) Q63531, (Mouse) P18653
Entrez Gene ID: (Chicken) 386579, (Human) 6195, (Chinese hamster) 100770849, (Rat) 81771, (Mouse) 20111, (Zebrafish) 777728, (Xenopus) 445821
Molecular Function:
non-receptor serine/threonine protein kinase
protein modifying enzyme
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