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Phospho-eIF2 beta (Ser67) Antibody (PA5-118774) in IHC (P)
Immunohistochemical analysis of Phospho-eIF2 beta (Ser67) in Mouse testis tissue using a Phospho-eIF2 beta (Ser67) polyclonal antibody (Product # PA5-118774). The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the primary antibody at 4°C overnight. An HRP conjugated anti-Rabbit antibody was used as the ... View More
Product Details
PA5-118774
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human EIF2S2(Accession P20042), corresponding to amino acid residues around phosphorylated Ser67.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
sequential chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2903274
Product Specific Information
Antibody detects endogenous levels of EIF2S2 only when phosphorylated at Ser67.
Target Information
Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits, alpha, beta, and gamma, with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP, which recycles the EIF-2 complex for another round of initiation. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: eIF-2-beta; eIF2-beta; EIF2BA; Eukaryotic translation initiation factor 2 subunit 2; Eukaryotic translation initiation factor 2 subunit beta; eukaryotic translation initiation factor 2, subunit 2 (beta, 38kDa); eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa; protein phosphatase 1, regulatory subunit 67
Gene Aliases: 2810026E11Rik; 38kDa; AA408636; AA571381; AA986487; AW822225; D2Ertd303e; eIF-2-beta; EIF2; EIF2B; EIF2beta; EIF2S2; PPP1R67
UniProt ID: (Human) P20042, (Mouse) Q99L45
Entrez Gene ID: (Human) 8894, (Mouse) 67204
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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