Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
Immunogen sequence: EKVQYLTRSA IRRASTIEMP QQARQKLQNL
Phospholamban (PLB) is a 52 amino acid phosphoprotein which regulates the calcium pump of cardiac sarcoplasmic reticulum (SR). PLB is an oligomer of five identical subunits each having a cytoplasmic and transmembrane domain. The cytoplasmic domain (residues 1 to 25) contains the phosphorylation sites and is highly basic and readily cleaved by proteases whereas the transmembrane domain (residues 25 to 52) is mostly hydrophobic, protease resistant and stabilizes the pentamer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cardiac CMH18; Phospholamban; PLB
Gene Aliases: CMD1P; CMH18; PLB; PLN
UniProt ID: (Human) P26678
Entrez Gene ID: (Human) 5350
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