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Fabgennix
Pin1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PIN1-112AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide taken within amino acid region 118-168 on human peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 protein.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
PIN1 (Peptidylprolyl Cis/Trans Isomerase, NIMA-Interacting 1) is a Protein Coding gene. Diseases associated with PIN1 include Meibomian Cyst and Viral Exanthem. Among its related pathways are Transport of the SLBP independent Mature mRNA and Cytokine Signaling in Immune system. Gene Ontology (GO) annotations related to this gene include peptidyl-prolyl cis-trans isomerase activity and mitogen-activated protein kinase binding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EC 5.2.1.8; NIMA-interacting; parvulin PIN1; peptidyl-prolyl cis-trans isomerase Pin1; PPIase Pin1; prolyl isomerase; protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1; protein interacting with never in mitosis A1; rotamase Pin1; UBL5; unnamed protein product
Gene Aliases: 0610025L01Rik; D9Bwg1161e; DOD; UBL5
UniProt ID: (Human) Q13526, (Mouse) Q9QUR7
Entrez Gene ID: (Human) 5300, (Rat) 298696, (Mouse) 23988
peptidyl-prolyl cis-trans isomerase activity
motor activity
protein binding
beta-catenin binding
cis-trans isomerase activity
mitogen-activated protein kinase kinase binding
GTPase activating protein binding
tau protein binding
phosphoserine binding
phosphothreonine binding
phosphoprotein binding
ubiquitin ligase activator activity
isomerase activity
protein peptidyl-prolyl isomerization
response to hypoxia
positive regulation of protein phosphorylation
Rho protein signal transduction
regulation of gene expression
neuron differentiation
negative regulation of transforming growth factor beta receptor signaling pathway
regulation of protein stability
protein destabilization
regulation of cytokinesis
regulation of cell proliferation
negative regulation of protein catabolic process
negative regulation of neuron apoptotic process
positive regulation of neuron apoptotic process
positive regulation of transcription from RNA polymerase II promoter
microtubule polymerization
synapse organization
protein stabilization
negative regulation of SMAD protein import into nucleus
positive regulation of cell growth involved in cardiac muscle cell development
negative regulation of ERK1 and ERK2 cascade
protein localization to mitochondrion
cellular response to hypoxia
positive regulation of canonical Wnt signaling pathway
regulation protein catabolic process at postsynapse
regulation of protein localization to nucleus
negative regulation of beta-amyloid formation
negative regulation of brown fat cell differentiation
negative regulation of cell motility
regulation of mitotic nuclear division
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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