PA5-29777 targets Pirin in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-29777 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 269 of Human Pirin.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This gene encodes a member of the cupin superfamily. The encoded protein is an Fe(II)-containing nuclear protein expressed in all tissues of the body and concentrated within dot-like subnuclear structures. Interactions with nuclear factor I/CCAAT box transcription factor as well as B cell lymphoma 3-encoded oncoprotein suggest the encoded protein may act as a transcriptional cofactor and be involved in the regulation of DNA transcription and replication. Alternatively spliced transcript variants have been described.
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Protein Aliases: 3-dioxygenase PIR; iron-binding nuclear protein; Pirin; pirin (iron-binding nuclear protein); pirin like; probable quercetin 2; Probable quercetin 2,3-dioxygenase PIR; Probable quercetinase
Gene Aliases: 2310042L19Rik; PIR; Pirnl