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Invitrogen
Pleckstrin Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-76903
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant full length Human Pleckstrin.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
Major protein kinase C substrate of platelets.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: contains PH domain at both N and C terminus; major substrate of protein kinase C; FLJ27168; platelet 47 kDa protein; PLEK; unnamed protein product
Gene Aliases: 2010300B13Rik; P47; PLEK1
UniProt ID: (Human) P08567, (Rat) Q4KM33, (Mouse) Q9JHK5
Entrez Gene ID: (Human) 5341, (Rat) 364206, (Mouse) 56193
hematopoietic progenitor cell differentiation
platelet degranulation
phospholipase C-activating G-protein coupled receptor signaling pathway
integrin-mediated signaling pathway
positive regulation of platelet activation
negative regulation of inositol phosphate biosynthetic process
actin cytoskeleton organization
positive regulation of actin filament depolymerization
phospholipase C-inhibiting G-protein coupled receptor signaling pathway
cortical actin cytoskeleton organization
ruffle organization
positive regulation of actin filament bundle assembly
positive regulation of integrin activation
intracellular signal transduction
inositol phosphate metabolic process
positive regulation of cellular component biogenesis
negative regulation of G-protein coupled receptor protein signaling pathway
regulation of cell diameter
thrombin receptor signaling pathway
negative regulation of thrombin receptor signaling pathway
platelet aggregation
protein secretion by platelet
cell projection organization
negative regulation of calcium-mediated signaling
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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