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Plectin Antibody (A304-506A) in WB
Detection of human and mouse Plectin by western blot. Samples: Whole cell lysate from 293T (15 and 50 µg), HeLa (15 µg), Jurkat (15 µg), and mouse TCMK-1 (15 µg) cells prepared using NETN and RIPA lysis buffer. Antibodies: Affinity purified rabbit anti-Plectin antibody (Product # A304-506A) (lot A304-506A-1) used for WB at 0.4 µg/mL. Detection: Chemiluminescence with an exposure time of 30 seconds.
Product Details
A304-506A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 4534 to 4684 of Human Plectin.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
phosphate/tris citrate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4° C
Shipping conditions
Wet ice
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.^M
^M
Based on 100% sequence identity, this antibody is predicted to react with Rat
Target Information
Plectin is a prominent member of an important family of structurally and in part functionally related proteins, termed plakins or cytolinkers, that are capable of interlinking different elements of the cytoskeleton. Plakins, with their multi-domain structure and enormous size, not only play crucial roles in maintaining cell and tissue integrity and orchestrating dynamic changes in cytoarchitecture and cell shape, but also serve as scaffolding platforms for the assembly, positioning, and regulation of signaling complexes. Plectin is expressed as several protein isoforms in a wide range of cell types and tissues from a single gene located on chromosome 8 in humans. The expression of specific plectin isoforms was found to be dependent on cell type (tissue) and stage of development and it appears that each cell type (tissue) contains a unique set (proportion and composition) of plectin isoforms which carry out distinct and specific functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HD1; Hemidesmosomal protein 1; PCN; Plectin; plectin 1; plectin 1, intermediate filament binding protein 500kDa; Plectin-1; Plectin-6
Gene Aliases: AA591047; AU042537; EBS1; EBSMD; EBSND; EBSO; EBSOG; EBSPA; HD1; LGMD2Q; PCN; PLEC; PLEC1; PLEC1b; PLTN
UniProt ID: (Human) Q6S380, (Mouse) Q9QXS1
Entrez Gene ID: (Human) 5339, (Mouse) 18810
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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