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PA1-31961 detects FBI1 from human samples.
PA1-31961 has been successfully used in Western blot applications.
The PA1-31961 immunogen is: Synthetic peptide: GAATDGNFTAGLA (Human).
Plays a key role in the instruction of early lymphoid progenitors to develop into B lineage by repressing T-cell instructive Notch signals. Specifically represses the transcription of the CDKN2A gene. Efficiently abrogates E2F1-dependent CDKN2A transactivation/de-repression. Binds to the consensus sequence 5'-[GA][CA]GACCCCCCCCC-3'.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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