|Immunocytochemistry (ICC)||Assay dependent|
|Immunofluorescence (IF)||Assay dependent|
|Western Blot (WB)||Assay dependent|
|Tested Species reactivity||Human, Mouse, Pig, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A protein specific peptide conjugated to KLH recognizing extracellualar epitopes.|
|Storage buffer||whole serum|
|Contains||0.05% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA3-881 detects progestin receptor beta in mouse, rat, human, and porcine cells.
PA3-881 has been successfully used in Western blotting and immunofluorescence procedures. By Western blot it detects a 40 kDa protein representing PR beta.
The PA3-881 immunogen is a protein specific peptide sequence conjugated to KLH, recognizing extracellular epitopes.
Progestin Receptor Beta-extra recognizes the extracellular epitope of the membrane progestin receptor. Progestin receptors with are found in pituitary, reproductive tract and most estrogen receptor-containing brain regions; these receptors are inducible by estrogen treatment. There are also progestin receptor sites in brain areas lacking estrogen receptors, such as the cerebral cortex of the rat; these receptors are not induced by estradiol treatment. Nevertheless, such receptors resemble those induced by estradiol. Another inducer of progestin receptors in brain is testosterone, which works through its conversion to estradiol via aromatization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Lysosomal membrane protein in brain 1; lysosomal membrane protein in brain-1; Membrane progestin receptor beta; mPR beta; Progestin and adipoQ receptor family member 8; Progestin and adipoQ receptor family member VIII; progestin membrane receptor beta; putative membrane steroid receptor
Gene Aliases: 1700019B16Rik; 3110001D06Rik; C6orf33; LMPB1; MPRB; PAQR8; Pmrbeta; RGD1311710
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