|Tested species reactivity||Human, Mouse, Pig, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A protein specific peptide conjugated to KLH recognizing extracellualar epitopes.|
|Storage buffer||whole serum|
|Contains||0.05% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunocytochemistry (ICC)||Assay dependent|
|Immunofluorescence (IF)||Assay dependent|
|Western Blot (WB)||Assay dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA3-881 detects progestin receptor beta in mouse, rat, human, and porcine cells.
PA3-881 has been successfully used in Western blotting and immunofluorescence procedures. By Western blot it detects a 40 kDa protein representing PR beta.
The PA3-881 immunogen is a protein specific peptide sequence conjugated to KLH, recognizing extracellular epitopes.
Progestin Receptor Beta-extra recognizes the extracellular epitope of the membrane progestin receptor. Progestin receptors with are found in pituitary, reproductive tract and most estrogen receptor-containing brain regions; these receptors are inducible by estrogen treatment. There are also progestin receptor sites in brain areas lacking estrogen receptors, such as the cerebral cortex of the rat; these receptors are not induced by estradiol treatment. Nevertheless, such receptors resemble those induced by estradiol. Another inducer of progestin receptors in brain is testosterone, which works through its conversion to estradiol via aromatization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.