This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. The proprotein is cleaved to produce a light chain and a heavy chain which are associated by a disulfide bond. It is active on peptide linkages involving the carboxyl group of lysine or arginine.
Protein Aliases: CAP1; channel activating protease 1; Channel-activating protease 1; Prostasin; Prostasin heavy chain; Prostasin light chain; protease, serine, 8 (prostasin); Serine protease 8
Gene Aliases: 2410039E18Rik; AI313909; C79772; CAP1; fr; mCAP1; PROSTASIN; PRSS8
Molecular Function: serine protease