|ELISA (ELISA)||Assay Dependent|
|Immunoelectrophoresis (IE)||Assay Dependent|
|Tested Species reactivity||Human|
|Host / Isotype||Sheep / IgG|
|Immunogen||Prothrombin from human plasma.|
|Storage buffer||0.01M HEPES, pH 7.4, with 0.15M NaCl, 50% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA1-74093 detects Prothrombin from human samples.
PA1-74093 has been successfully used in ELISA and immunoelectrophoresis applications.
The PA1-74093 immunogen is prothrombin from human plasma.
Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: prepro-coagulation factor II; prothrombin; prothrombin B-chain; serine protease
Gene Aliases: PT; RPRGL2; THPH1
UniProt ID: (Human) P00734
Entrez Gene ID: (Human) 2147
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