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          • Primary Antibodies ›
          • QARS Antibodies

          Invitrogen

          QARS Polyclonal Antibody

          View all (11) QARS antibodies

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          Cite QARS Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (5)
          QARS Antibody in Immunocytochemistry (ICC/IF)
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          QARS Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 5

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          QARS Antibody (PA5-93316) in ICC/IF

          Immunofluorescence analysis of QARS in U2OS cells. Samples were incubated with QARS Polyclonal antibody (Product # PA5-93316). Blue: DAPI for nuclear staining. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          QARS Antibody in Immunocytochemistry (ICC/IF)
          QARS Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          QARS Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          QARS Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          QARS Antibody in Western Blot (WB)

          Product Details

          PA5-93316

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:200
          -

          Immunocytochemistry (ICC/IF)

          1:50-1:100
          -

          ELISA (ELISA)

          1 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human, Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein (or fragment)

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.49 mg/mL

          Amount

          49 µg

          Purification

          Affinity Chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2806713

          Product Specific Information

          Positive Samples: HL-60, 293T, HeLa, Mouse testis; Cellular Location: Cytoplasm

          Target Information

          Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. In metazoans, 9 aminoacyl-tRNA synthetases specific for glutamine (gln), glutamic acid (glu), and 7 other amino acids are associated within a multienzyme complex. Although present in eukaryotes, glutaminyl-tRNA synthetase (QARS) is absent from many prokaryotes, mitochondria, and chloroplasts, in which Gln-tRNA(Gln) is formed by transamidation of the misacylated Glu-tRNA(Gln). Glutaminyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: GlnRS; Glutamine--tRNA ligase; glutamine-tRNA ligase; glutamine-tRNA synthetase; Glutaminyl-tRNA synthetase; unnamed protein product

          View more View less

          Gene Aliases: 1110018N24Rik; 1200016L19Rik; C80286; GLNRS; MSCCA; PRO2195; QARS; QARS1

          View more View less

          UniProt ID: (Human) P47897, (Mouse) Q8BML9

          View more View less

          Entrez Gene ID: (Human) 5859, (Mouse) 97541

          View more View less

          Function(s)
          nucleotide binding aminoacyl-tRNA ligase activity glutamine-tRNA ligase activity protein kinase inhibitor activity protein binding ATP binding ligase activity protein kinase binding RNA binding aminoacyl-tRNA synthetase
          Process(es)
          translation tRNA aminoacylation for protein translation glutaminyl-tRNA aminoacylation brain development negative regulation of stress-activated MAPK cascade tRNA aminoacylation negative regulation of transcription, DNA-templated negative regulation of apoptotic signaling pathway negative regulation of apoptotic process
          It has to be done as per old AB suggested Products section.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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