Search
Proteintech
QDPR Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
14908-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
QDPR Fusion Protein Ag6705 (1-244 aa encoded by BC000576)
Conjugate
Form
Liquid
Concentration
0.21 mg/mL
Amount
31.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAAAAAAGE ARRVLVYGGR GALGSRCVQA FRARNWWVAS VDVVENEEAS ASIIVKMTDS FTEQADQVTA EVGKLLGEEK VDAILCVAGG WAGGNAKSKS LFKNCDLMWK QSIWTSTISS HLATKHLKEG GLLTLAGAKA ALDGTPGMIG YGMAKGAVHQ LCQSLAGKNS GMPPGAAAIA VLPVTLDTPM NRKSMPEADF SSWTPLEFLV ETFHDWITGK NRPSSGSLIQ VVTTEGRTEL TPAYF (1-244 aa encoded by BC000576)
Target Information
This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 6,7-dihydropteridine reductase; Dihydropteridine reductase; dihydropteridine reductase (EC 1.6.99.7); HDHPR; HPR; Quinoid dihydropteridine reductase; Short chain dehydrogenase/reductase family 33C member 1; testis secretory sperm-binding protein Li 236P; unnamed protein product
Gene Aliases: 2610008L04Rik; D5Ertd371e; DHPR; HDHPR; PKU2; QDPR; SDR33C1
UniProt ID: (Human) P09417, (Rat) P11348, (Mouse) Q8BVI4
Entrez Gene ID: (Human) 5860, (Rat) 64192, (Mouse) 110391
cellular amino acid metabolic process
L-phenylalanine catabolic process
tetrahydrobiopterin biosynthetic process
pteridine-containing compound metabolic process
dihydrobiopterin metabolic process
liver development
response to aluminum ion
response to lead ion
response to glucagon
cellular response to drug
oxidation-reduction process
metabolic process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support