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Proteintech
QDPR Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
14908-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
QDPR Fusion Protein Ag6705 (1-244 aa encoded by BC000576)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.21 mg/mL
Amount
31.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAAAAAAGE ARRVLVYGGR GALGSRCVQA FRARNWWVAS VDVVENEEAS ASIIVKMTDS FTEQADQVTA EVGKLLGEEK VDAILCVAGG WAGGNAKSKS LFKNCDLMWK QSIWTSTISS HLATKHLKEG GLLTLAGAKA ALDGTPGMIG YGMAKGAVHQ LCQSLAGKNS GMPPGAAAIA VLPVTLDTPM NRKSMPEADF SSWTPLEFLV ETFHDWITGK NRPSSGSLIQ VVTTEGRTEL TPAYF (1-244 aa encoded by BC000576)
Target Information
This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 6,7-dihydropteridine reductase; dihydropteridine reductase (EC 1.6.99.7); HDHPR; HPR; short chain dehydrogenase/reductase family 33C member 1; testis secretory sperm-binding protein Li 236P; unnamed protein product
Gene Aliases: 2610008L04Rik; D5Ertd371e; DHPR; HDHPR; PKU2; SDR33C1
UniProt ID: (Human) P09417, (Mouse) Q8BVI4, (Rat) P11348
Entrez Gene ID: (Human) 5860, (Mouse) 110391, (Rat) 64192
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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