Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Recommended positive controls: Jurkat, mouse liver.
Predicted reactivity: Mouse (94%), Rat (96%), Pig (94%), Rabbit (95%), Chicken (83%), Bovine (92%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 6,7-dihydropteridine reductase; Dihydropteridine reductase; HDHPR; HPR; Quinoid dihydropteridine reductase; Short chain dehydrogenase/reductase family 33C member 1; short chain dehydrogenase/reductase family 33C, member 1; testis secretory sperm-binding protein Li 236P
Gene Aliases: 2610008L04Rik; D5Ertd371e; DHPR; PKU2; QDPR; SDR33C1
UniProt ID: (Human) P09417, (Mouse) Q8BVI4
Entrez Gene ID: (Human) 5860, (Mouse) 110391
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