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Invitrogen
QDPR Polyclonal Antibody
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Product Details
PA5-28041
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human QDPR. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.92 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: Jurkat, mouse liver.
Predicted reactivity: Mouse (94%), Rat (96%), Pig (94%), Rabbit (95%), Chicken (83%), Bovine (92%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 6,7-dihydropteridine reductase; Dihydropteridine reductase; HDHPR; HPR; Quinoid dihydropteridine reductase; Short chain dehydrogenase/reductase family 33C member 1; short chain dehydrogenase/reductase family 33C, member 1; testis secretory sperm-binding protein Li 236P
Gene Aliases: 2610008L04Rik; D5Ertd371e; DHPR; PKU2; QDPR; SDR33C1
UniProt ID: (Human) P09417, (Mouse) Q8BVI4
Entrez Gene ID: (Human) 5860, (Mouse) 110391
liver development
cellular amino acid metabolic process
L-phenylalanine catabolic process
tetrahydrobiopterin biosynthetic process
response to aluminum ion
response to lead ion
response to glucagon
cellular response to drug
dihydrobiopterin metabolic process
oxidation-reduction process
metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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