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|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 106 and 341 of Human QK1|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Frozen) (IHC (F))||1:100-1:1000|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-30563 targets QK1 in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-30563 immunogen is recombinant fragment corresponding to a region within amino acids 106 and 341 of Human QK1.
QKI belongs to a family of RNA-binding proteins that have an HNRNPK (MIM 600712) homology (KH) domain embedded in a 200-amino acid region called the GSG domain. Other members of this family include SAM68 (KHDRBS1; MIM 602489) and SF1 (MIM 601516) (Chen and Richard, 1998 [PubMed 9671495]). QKI proteins regulate RNA splicing, export of target RNAs from the nucleus, translation of proteins, and RNA stability (Lauriat et al., 2008 [PubMed 17918747]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
homolog of mouse quaking QKI (KH domain RNA binding protein); hqkI; KH domain RNA binding; lethal, Chr 17, U Wisconsin 1; protein quaking; QK; QK1; QK3; QKI, KH domain containing, RNA binding; QKI-5 protein; quaking homolog; quaking homolog, KH domain RNA binding; RNA binding protein HQK
1110003F05Rik; 1500005P18; HKQ; Hqk; hqkI; l(17)-1Wis; l17Wis1; QK; QK1; QK3; Qka1; QKI