This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: ALVDSWLRED CPGLNYAALV SGAGPSQAAL WAKSPGVLAG QPFFDAIFTQ LNCQVSWFLP EGSKLVPVAR VAEVRGPAHC LLLGERVALN TLARCSGIAS AAAAAVEAAR GAGWTGHVAG TRKTTPGFRL V
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 84%.
QPRT gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: epididymis secretory sperm binding protein Li 90n; nicotinate-nucleotide pyrophosphorylase (carboxylating); Nicotinate-nucleotide pyrophosphorylase [carboxylating]; QAPRTase; QPRT; QPRTase; Quinolinate phosphoribosyltransferase [decarboxylating]
Gene Aliases: HEL-S-90n; QPRT; QPRTase
UniProt ID: (Human) Q15274
Entrez Gene ID: (Human) 23475