Immunogen sequence: CSACHNERLDV PVWDVEATLN FLKAHFSPSN IILDFPAAGS AARRDVQNVA AAPELAMGAL ELESRNSTLD P
Highest antigen sequence identity to the following orthologs - mouse 58%, rat 59%.
The QSOX1 gene, also known as Quiescin Q6, is a fusion of two ancient genes: thioredoxin and ERV1. Its expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation. The QSOX1 protein oxidizes sulfhydryl groups to form disulfide bonds in proteins. QSOX1 expression is induced by hypoxia and appears to protect cells against oxidative stress-induced apoptosis.
Protein Aliases: hQSOX; Quiescin Q6; quiescin Q6 sulfhydryl oxidase 1; RP11-502H18.3; Sulfhydryl oxidase 1; testis tissue sperm-binding protein Li 62n; thiol oxidase 1
Gene Aliases: Q6; QSCN6; QSOX1; UNQ2520/PRO6013
UniProt ID: (Human) O00391
Entrez Gene ID: (Human) 5768