Fabgennix

Quiescin Q6 Polyclonal Antibody, FITC

Product Details

QSOX1-FITC

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:1,000	-
Immunohistochemistry (IHC)	1:50-1:250	-
ELISA (ELISA)	1:10,000	-
Immunoprecipitation (IP)	1:50-1:250	-

Product Specifications
Species Reactivity	Human, Rat
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	Synthetic peptide corresponding to unique amino acid sequence on human QSOX1 protein.
Conjugate	FITC
Excitation/Emission Max	498/517 nm View spectra
Form	Liquid
Concentration	0.5-1.5 mg/mL
Purification	Affinity chromatography
Storage buffer	proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
Contains	0.02% sodium azide
Storage conditions	-20° C, store in dark

Target Information

The QSOX1 gene, also known as Quiescin Q6, is a fusion of two ancient genes: thioredoxin and ERV1. Its expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation. The QSOX1 protein oxidizes sulfhydryl groups to form disulfide bonds in proteins. QSOX1 expression is induced by hypoxia and appears to protect cells against oxidative stress-induced apoptosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: FAD-dependent sulfhydryl oxidase-2; hQSOX; Quiescin Q6; quiescin Q6 sulfhydryl oxidase 1; RP11-502H18.3; rQSOX; SOx-2; Sulfhydryl oxidase 1; testis tissue sperm-binding protein Li 62n; thiol oxidase 1

Gene Aliases: Q6; QSCN6; Qsox; QSOX1; rSOx; Sox-2; Sox2; UNQ2520/PRO6013

UniProt ID: (Human) O00391, (Rat) Q6IUU3

Entrez Gene ID: (Human) 5768, (Rat) 84491

Molecular Function: oxidase