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RAB10 Polyclonal Antibody

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RAB10 Antibody in Western Blot (WB) — Mouse brain tissue were subjected to SDS PAGE followed by western blot with 11808-1-AP ( RAB10 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

Product Details

11808-1-AP

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:2,000	View 11 publications 11 publications
Immunohistochemistry (IHC)	Assay-dependent	View 1 publication 1 publication
Immunocytochemistry (ICC/IF)	-	View 4 publications 4 publications
Immunoprecipitation (IP)	Assay-dependent	View 1 publication 1 publication
Miscellaneous PubMed (Misc)	-	View 1 publication 1 publication

Product Specifications
Species Reactivity	Human, Mouse, Rat
Published species	Human, Mouse, Rat, Zebrafish
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	RAB10 Fusion Protein Ag2473 (1-200 aa encoded by BC000896) View immunogen
Conjugate	Unconjugated
Form	Liquid
Concentration	0.27 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.3, with 50% glycerol
Contains	0.1% sodium azide
Storage conditions	-20°C

Product Specific Information

Immunogen sequence: MAKKTYDLL FKLLLIGDSG VGKTCVLFRF SDDAFNTTFI STIGIDFKIK TVELQGKKIK LQIWDTAGQE RFHTITTSYY RGAMGIMLVY DITNGKSFEN ISKWLRNIDE HANEDVERML LGNKCDMDDK RVVPKGKGEQ IAREHGIRFF ETSAKANINI EKAFLTLAED ILRKTPVKEP NSENVDISSG GGVTGWKSKC C (1-200 aa encoded by BC000896)

Target Information

RAB10 belongs to the RAS superfamily of small GTPases. RAB proteins localize to exocytic and endocytic compartments and regulate intracellular vesicle trafficking.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Long noncoding RNA AFAP1-AS1 acts as a competing endogenous RNA of miR-423-5p to facilitate nasopharyngeal carcinoma metastasis through regulating the Rho/Rac pathway.

Journal of experimental & clinical cancer research : CR

Lian Y,Xiong F,Yang L,Bo H,Gong Z,Wang Y,Wei F,Tang Y,Li X,Liao Q,Wang H,Zhou M,Xiang B,Wu X,Li Y,Li X,Chen X,Li G,Guo C,Zeng Z,Xiong W

Tue Oct 16 00:00:00 EDT 2018

Rab10 Disruption Results in Delayed OPC Maturation.

Cellular and molecular neurobiology

Zhang ZH,Zhao WQ,Ma FF,Zhang H,Xu XH

Sun Oct 01 00:00:00 EDT 2017

MARCKS is Necessary for Oligodendrocyte Precursor Cell Maturation.

Neurochemical research

Zhang ZH,Ma FF,Zhang H,Xu XH

Sun Oct 01 00:00:00 EDT 2017

MARCKS is Necessary for Oligodendrocyte Precursor Cell Maturation.

Neurochemical research

Zhang ZH,Ma FF,Zhang H,Xu XH

Sun Oct 01 00:00:00 EDT 2017

Quantitative proteome analysis of colorectal cancer-related differential proteins.

Journal of cancer research and clinical oncology

Zhang Y,Liu Y,Ye Y,Shen D,Zhang H,Huang H,Li S,Wang S,Ren J

Wed Feb 01 00:00:00 EST 2017

AFAP1-AS1, a long noncoding RNA upregulated in lung cancer and promotes invasion and metastasis.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Zeng Z,Bo H,Gong Z,Lian Y,Li X,Li X,Zhang W,Deng H,Zhou M,Peng S,Li G,Xiong W

Fri Jan 01 00:00:00 EST 2016

Upregulated long non-coding RNA AFAP1-AS1 expression is associated with progression and poor prognosis of nasopharyngeal carcinoma.

Oncotarget

Bo H,Gong Z,Zhang W,Li X,Zeng Y,Liao Q,Chen P,Shi L,Lian Y,Jing Y,Tang K,Li Z,Zhou Y,Zhou M,Xiang B,Li X,Yang J,Xiong W,Li G,Zeng Z

Fri Aug 21 00:00:00 EDT 2015

Semaphorin 3A activates the guanosine triphosphatase Rab5 to promote growth cone collapse and organize callosal axon projections.

Science signaling

Wu KY,He M,Hou QQ,Sheng AL,Yuan L,Liu F,Liu WW,Li G,Jiang XY,Luo ZG

Tue Aug 26 00:00:00 EDT 2014

MARCKS regulates membrane targeting of Rab10 vesicles to promote axon development.

Cell research

Xu XH,Deng CY,Liu Y,He M,Peng J,Wang T,Yuan L,Zheng ZS,Blackshear PJ,Luo ZG

Thu May 01 00:00:00 EDT 2014

MARCKS regulates membrane targeting of Rab10 vesicles to promote axon development.

Cell research

Xu XH,Deng CY,Liu Y,He M,Peng J,Wang T,Yuan L,Zheng ZS,Blackshear PJ,Luo ZG

Thu May 01 00:00:00 EDT 2014

MARCKS regulates membrane targeting of Rab10 vesicles to promote axon development.

Cell research

Xu XH,Deng CY,Liu Y,He M,Peng J,Wang T,Yuan L,Zheng ZS,Blackshear PJ,Luo ZG

Thu May 01 00:00:00 EDT 2014

JIP1 mediates anterograde transport of Rab10 cargos during neuronal polarization.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Deng CY,Lei WL,Xu XH,Ju XC,Liu Y,Luo ZG

Wed Jan 29 00:00:00 EST 2014

JIP1 mediates anterograde transport of Rab10 cargos during neuronal polarization.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Deng CY,Lei WL,Xu XH,Ju XC,Liu Y,Luo ZG

Wed Jan 29 00:00:00 EST 2014

Myosin Vb controls biogenesis of post-Golgi Rab10 carriers during axon development.

Nature communications

Liu Y,Xu XH,Chen Q,Wang T,Deng CY,Song BL,Du JL,Luo ZG

Mon Dec 30 00:00:00 EST 2013

Myosin Vb controls biogenesis of post-Golgi Rab10 carriers during axon development.

Nature communications

Liu Y,Xu XH,Chen Q,Wang T,Deng CY,Song BL,Du JL,Luo ZG

Mon Dec 30 00:00:00 EST 2013

Adaptor protein complex 2-mediated, clathrin-dependent endocytosis, and related gene activities, are a prominent feature during maturation stage amelogenesis.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Lacruz RS,Brookes SJ,Wen X,Jimenez JM,Vikman S,Hu P,White SN,Lyngstadaas SP,Okamoto CT,Smith CE,Paine ML

Fri Mar 01 00:00:00 EST 2013

Quantitative analysis of synaptic vesicle Rabs uncovers distinct yet overlapping roles for Rab3a and Rab27b in Ca2+-triggered exocytosis.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Pavlos NJ,Grønborg M,Riedel D,Chua JJ,Boyken J,Kloepper TH,Urlaub H,Rizzoli SO,Jahn R

Wed Oct 06 00:00:00 EDT 2010

Proceedings of the National Academy of Sciences of the United States of America

Wang D,Lou J,Ouyang C,Chen W,Liu Y,Liu X,Cao X,Wang J,Lu L

Tue Aug 03 00:00:00 EDT 2010

Identification of transgelin-2 as a biomarker of colorectal cancer by laser capture microdissection and quantitative proteome analysis.

Cancer science

Zhang Y,Ye Y,Shen D,Jiang K,Zhang H,Sun W,Zhang J,Xu F,Cui Z,Wang S

Mon Feb 01 00:00:00 EST 2010

Bioinformatics

Protein Aliases: GTP-binding protein RAB10; ras-related GTP-binding protein; Ras-related protein Rab-10; ras-related protein rab10

Gene Aliases: Ac1075; AW107754; RAB10

UniProt ID: (Human) P61026, (Mouse) P61027

Entrez Gene ID: (Human) 10890, (Mouse) 19325, (Rat) 50993

Function(s)

transport intracellular protein transport Golgi to plasma membrane transport vesicle docking involved in exocytosis small GTPase mediated signal transduction axonogenesis metabolic process protein secretion protein transport vesicle-mediated transport endosomal transport regulation of exocytosis antigen processing and presentation Rab protein signal transduction cellular response to insulin stimulus establishment of neuroblast polarity endoplasmic reticulum tubular network organization protein localization to plasma membrane establishment of protein localization to membrane establishment of protein localization to endoplasmic reticulum membrane polarized epithelial cell differentiation Golgi to plasma membrane protein transport basolateral protein localization cellular response to antibiotic membrane organization cell-cell adhesion

Process(es)

GTPase activity protein binding GTP binding GDP binding myosin V binding cadherin binding involved in cell-cell adhesion nucleotide binding molecular_function

RAB10 Polyclonal Antibody

Product Details

11808-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Miscellaneous PubMed (Misc)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Product Specific Information

Target Information

Bioinformatics

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