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Proteintech
RAB11B Polyclonal Antibody
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Product Details
19742-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Dog,
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide
Conjugate
Form
Liquid
Concentration
0.27 mg/mL
Amount
40.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
The antibody is specific to RAB11B. The antibody has no cross reaction to RAB11A.
Target Information
Rab proteins are low-molecular-weight GTP-binding proteins that form the largest branch of the Ras superfamily of GTPases. Located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Three membrane proteins, synaptosomal associated protein of 25 kDa (SNAP-25), synaptobrevin, and syntaxin, form the core of a ubiquitous membrane fusion machine that interacts with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and a-SNAP. Rab proteins, in coordination with the core fusion machinery and Munc-18, help to mediate vesicle docking and fusion. There exist over 40 Rab proteins that have been described in mammals. Rab 11 is a known marker for protein trafficking, sorting, and recycling in the endosomal pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: GTP-binding protein YPT3; RAB11B; RAB11B, member of RAS oncogene family; RAS oncogene family protein; Ras-related protein Rab-11B; unnamed protein product; YPT3
Gene Aliases: A730055L17Rik; H-YPT3; NDAGSCW; RAB11B; YPT3
UniProt ID: (Human) Q15907, (Rat) O35509, (Mouse) P46638
Entrez Gene ID: (Human) 9230, (Rat) 79434, (Mouse) 19326
receptor recycling
intracellular protein transport
endocytosis
melanosome transport
Rab protein signal transduction
transferrin transport
insulin secretion involved in cellular response to glucose stimulus
regulation of anion transport
constitutive secretory pathway
regulated exocytosis
cellular response to acidic pH
establishment of protein localization to membrane
retrograde transport, endosome to plasma membrane
regulation of protein localization to cell surface
regulation of endocytic recycling
protein transport
endocytic recycling
vesicle-mediated transport to the plasma membrane
amyloid-beta clearance by transcytosis
transport
small GTPase mediated signal transduction
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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