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Proteintech
RAB11B Polyclonal Antibody
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Product Details
28498-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RAB11B Fusion Protein Ag25429
Conjugate
Form
Liquid
Concentration
200 µg/mL
Amount
30 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Aliquoting is unnecessary for -20°C storage.
Target Information
Rab proteins are low-molecular-weight GTP-binding proteins that form the largest branch of the Ras superfamily of GTPases. Located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Three membrane proteins, synaptosomal associated protein of 25 kDa (SNAP-25), synaptobrevin, and syntaxin, form the core of a ubiquitous membrane fusion machine that interacts with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and a-SNAP. Rab proteins, in coordination with the core fusion machinery and Munc-18, help to mediate vesicle docking and fusion. There exist over 40 Rab proteins that have been described in mammals. Rab 11 is a known marker for protein trafficking, sorting, and recycling in the endosomal pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: GTP-binding protein YPT3; RAB11B; RAB11B, member of RAS oncogene family; RAS oncogene family protein; Ras-related protein Rab-11B; unnamed protein product; YPT3
Gene Aliases: A730055L17Rik; H-YPT3; NDAGSCW; RAB11B; YPT3
UniProt ID: (Human) Q15907, (Mouse) P46638
Entrez Gene ID: (Human) 9230, (Mouse) 19326
receptor recycling
protein transport
melanosome transport
endocytic recycling
transferrin transport
insulin secretion involved in cellular response to glucose stimulus
regulation of anion transport
constitutive secretory pathway
regulated exocytosis
cellular response to acidic pH
establishment of protein localization to membrane
vesicle-mediated transport to the plasma membrane
amyloid-beta clearance by transcytosis
regulation of protein localization to cell surface
regulation of endocytic recycling
transport
intracellular protein transport
endocytosis
small GTPase mediated signal transduction
Rab protein signal transduction
retrograde transport, endosome to plasma membrane
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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